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目的:探讨体外受精-胚胎移植(IVF-ET)中移植2枚胚胎后发生三胎妊娠行单绒毛膜双胎中一胎减灭术后的妊娠结局。方法:回顾性分析27例行单绒毛膜双胎中一胎减灭术的三胎妊娠患者的临床资料,了解术后一般情况,并对比术后仍保留双胎妊娠的与同期非减胎双胎妊娠的妊娠结局及新生儿情况。结果:减胎术后有12例(44.44%)发生自然减灭仅留一胎;保留双胎组与非减胎双胎组患者平均年龄、平均孕周及平均胎儿出生体质量无统计学差异(P>0.05);早期均无流产发生,晚期流产率分别为6.67%和10.00%,抱婴回家率分别为93.33%、90.00%,早产率分别为21.43%和37.04%,低体质量儿出生比例分别为21.43%和33.33%,围产儿死亡率分别为0.0%和3.7%,组间均无统计学差异(P>0.05),减胎后双胎组和非减胎双胎组均无畸形儿出生。结论:行减灭单绒毛膜双胎中一胎的减胎术有近一半的患者另一胎会发生自然减灭,余保留双胎的妊娠结局和新生儿一般情况与非减胎双胎妊娠组无统计学差异。
OBJECTIVE: To investigate the pregnancy outcomes of single-chorionic twins in single-chorionic twins after three embryo transfer in vitro fertilization-embryo transfer (IVF-ET). Methods: Retrospective analysis of 27 cases of single chorionic twins in the reduction of one child fetal triple pregnancy clinical data to understand the general situation after surgery, and still retained after the twin pregnancy non-fetal double Pregnancy outcome of pregnancy and newborns. Results: Twelve cases (44.44%) had spontaneous hypothyroidism and only one child died after the operation. There was no significant difference in average age, average gestational age and average fetus birth weight between the twins and non-twins (P> 0.05). No abortion occurred in the early stage, and the rate of late abortion was 6.67% and 10.00% respectively. The rate of returning to infancy was 93.33% and 90.00%, respectively. The rates of premature delivery were 21.43% and 37.04% The birth rates were 21.43% and 33.33% respectively. The perinatal mortality rates were 0.0% and 3.7% respectively. There was no significant difference between the two groups (P> 0.05) Deformity child was born. CONCLUSIONS: Approximately half of all pregnancies in a single abortion in a single choriocapillaris abortion are subject to natural abatement, leaving more than one pregnancy outcome and normal neonatal status with non-aborted twin pregnancies No significant difference between groups.