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曾有文献报道抗组织胺药与拟交感神经药合用以减轻感冒症状疗效较各自单用为佳,故作者将两药制成复合剂进行了双盲对照研究以验证其对减轻感冒病人鼻、耳症状的效果并观察其在门诊使用时的副作用。自愿受试者92人(女71、男21),随机分为试验组和对照组。前者接受持续缓慢释放的右旋氯苯吡胺(dexchlorpheniramine)和假麻黄碱复合剂,对照组用安慰剂。所有受试者必须有急性鼻炎症状。在发病48小时内给药,每天早晚各服一片,连服五天为一疗程,进行了二个疗程治疗观察。由于多种原因有12人退出,80人完成了治疗研究,其中39人(女29、男10)服药,41人
It has been reported in the literature that the combination of antihistamine and sympathomimetic drugs to reduce the symptoms of cold symptoms are better than their own single use, so the author made a double-blind controlled-dose combination of two drugs to verify its effect on reducing nasal, Ear symptoms and observe its side effects when used in the clinic. 92 volunteers (female 71, male 21) were randomly divided into experimental group and control group. The former received sustained and slow release of dexchlorpheniramine and pseudoephedrine complex, the control group with placebo. All subjects must have acute rhinitis symptoms. Within 48 hours of onset of medication, morning and evening, each serving a piece, and even served five days for a course of treatment for two courses of treatment observation. Twelve people withdrew for various reasons and 80 completed the treatment study, of which 39 (female 29, male 10) and 41