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脱屑性间质性肺炎(Desquamative interstitial pneumonia,简称DIP)是一种原因未明的特殊类型的间质性肺炎。此病病变特点是大量肺泡上皮增生并脱落于肺泡腔及细支气管腔内,肺泡壁增厚,有单核细胞,淋巴细胞等浸润。本病可发生于任何年龄,幼儿亦可受累,但以中年、青年为主。临床症状有呼吸困难、干咳、声嘶、紫绀、杵状指、体重减轻等,x线可见肺野模糊不清,呈毛玻璃样密度。本病常需肺活组织检查才能确诊,多数病人用皮质激素治疗有效。
Desquamative interstitial pneumonia (DIP) is an unexplained type of interstitial pneumonia. The lesion is characterized by a large number of alveolar epithelial hyperplasia and fall off in the alveolar cavity and bronchioles, alveolar wall thickening, mononuclear cells, lymphocytes and other infiltration. The disease can occur at any age, children may also be involved, but mainly middle-aged and young people. Clinical symptoms are dyspnea, dry cough, hoarseness, cyanosis, clubbing, weight loss, etc., lung field can be blurred vision, was frosted glass-like density. The disease often require lung biopsy to confirm the diagnosis, most patients with corticosteroids effective.