血管扩张剂是治疗心力衰竭的一类重要药物,在治疗中常与其他药物合并应用,但有时如合用不当,反可发生毒副作用;为了合理、有效、安全的合并用药,现将其药物相互作用综述如下。一、硝酸甘油和二硝酸异山梨醇二者能松弛平滑肌而扩张血管,使左心室充盈压、肺楔嵌压和右心房压明显降低。前者用于治疗急性 Vasodilators are an important class of drugs for the treatment of heart failure. They are often used in combination with other drugs in the treatment, but sometimes they can cause side effects if used improperly. In order to be rational, effective and safe, drug-drug interactions Summarized as follows. First, both nitroglycerin and isosorbide dinitrate can relax smooth muscle and dilate blood vessels, so that left ventricular filling pressure, pulmonary wedge pressure and right atrial pressure decreased significantly. The former is used to treat acute