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作者应用小鼠模型,对接种两组分[百日咳类毒素(PT)和丝状血凝素(FHA)]、三组分〔PT、FHA和69kDa蛋白(PRN)〕和单组分(PRN)百日咳无细胞菌苗DTP的小鼠进行了亚致死量的气溶胶攻击及致死量和亚致死量的鼻腔攻击。所有实验均选用3~4周龄雌
The authors used the mouse model to test the inoculation of two components [pertussis toxoid (PT) and filamentous hemagglutinin (FHA)], three components [PT, FHA and 69 kDa protein (PRN) Mice of pertussis acellular bacterin DTP were challenged with sub-lethal aerosol challenge and lethal and sublethal nasal challenge. All experiments were selected 3 to 4 weeks old female