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目的:探讨持续性咳嗽儿童百日咳临床多中心调查研究。方法:随机抽取2013年5月~2015年5月我院收治的168例持续性咳嗽儿童患者的病例作为研究对象,通过回顾分析,主要采用百日咳博德特菌培养和多重PCR、ELISA等方法来对IgG(PTIgG)进行检测。结果:168例患者百日咳博德特菌感染率为12.43%,DPT疫苗的接种率高达95.32%,不同年龄的患者感染率不相同,年龄段不同的患者百日咳博德特菌感染率比较差异具有统计学意义(P<0.05)。结论:虽然对儿童与青少年进行了疫苗接种,但是,在临床中,百日咳博德特菌感染还是导致儿童持续性咳嗽的主要原因。
Objective: To investigate the clinical multicenter investigation of whooping cough in children with persistent cough. Methods: A total of 168 cases of persistent cough children treated in our hospital from May 2013 to May 2015 were selected as the research objects. By retrospective analysis, the methods of Bordetella pertussis culture and multiplex PCR and ELISA IgG (PTIgG) was tested. Results: 168 cases of Bordetella pertussis infection rate was 12.43%, DPT vaccine vaccination rate as high as 95.32%, different ages of patients with different rates of infection, age groups with different prevalence of Bordetella pertussis infection with statistics Significance (P <0.05). Conclusion: Although vaccination of children and adolescents, Bordetella pertussis infection is the leading cause of persistent cough in children in the clinic.