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为研究卵巢性雄激素过多症(OHA)少女胰腺β-细胞功能状态,45例年龄12～17岁少女纳入研究,其中20例体重正常OHA(1组),15例肥胖症OHA(2组),10例无OHA征象少女作对照组。研究患者家庭史及性成熟经过的病史资料,妇科检查评价生殖器官发育程度,确定体重指数,据腰/臀比值确定脂肪组织分布类型,超声检查盆腔器官,检测空腹血糖(血浆)和免疫反应胰岛素水平,在标准糖耐量试验(GTT)过程中每隔60min检测血糖和免疫反应胰岛素浓度,
In order to study the functional status of pancreatic β-cells in ovariectomized women with ovariectomized and hyperandrogenism (OHA), 45 age-12-17-year-old girls were enrolled in the study. Twenty normal OHA (group 1) and 15 obese OHA ), 10 cases without OHA girls as the control group. Study the history of patients with family history and sexual maturity, gynecological examination to assess the extent of genital development, to determine body mass index, according to waist / hip ratio to determine the distribution of adipose tissue, pelvic organ ultrasound examination, fasting blood glucose (plasma) and immune response to insulin Level, glucose and immunoreactive insulin concentrations were measured every 60 min during the standard glucose tolerance test (GTT)