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目的:了解新生儿短肠综合征(NSBS)的远期疗效以及评价各种术式。方法:手术治疗的9例与非手术治疗的5例共14例 NSBS,5种术式:小肠肠袢再循环术(1例)、小肠肠袢倒置术(2例)、小肠瓣膜成形术(2例)、小肠新粘膜再生术(3例)、结肠间置术(1例)。结果:经过5年以上的随访,手术组9例中8例存活,非手术组5例仅1例存活。小肠新粘膜再生术与结肠间置术的远期疗效最好。小肠肠袢再循环术与小肠肠袢倒置术3例中2例脂肪吸收不良。小肠瓣膜成形术2例中1例尿中尿兰母>100 mg/24h,说明蛋白质吸收尚未完全恢复。
Objective: To understand the long-term efficacy of short-term neonatal short bowel syndrome (NSBS) and evaluate various surgical procedures. Methods: A total of 14 NSBS patients underwent surgical treatment of 9 patients and 5 patients who underwent nonsurgical treatment. Five procedures were performed: one small intestine rectum (1 case), small intestine bowel inverted operation (2 cases), small bowel valvuloplasty 2 cases), small intestinal mucosa regeneration (3 cases) and colon interposition (1 case). Results: After 5 years of follow-up, 8 of 9 patients survived in the operation group and only 1 patient survived in 5 of the non-operation patients. Intestinal mucosal regeneration and colon interposition long-term efficacy of the best. Two cases of fat malabsorption were found in 3 cases of small bowel rectum and small intestine bowel. In 2 cases of small bowel valvuloplasty, 1 case of urine Ulania> 100 mg / 24h, indicating that the protein absorption has not yet fully recovered.