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从糖尿病昏迷时代经过感染时代,现在为血管病变时代。1922年胰岛素的发现以后昏迷的死亡急剧减少。1944年以来抗菌素的相继问世因感染而死亡者也减少。现在心血管病变的死因高达75％。日本最近统计糖尿病患者的死因,由于心、脑、肾血管病变所致者占40～50％。在日本糖尿病作为死因的血管病变的内容和美国不同,在美国主要是冠心病死亡(心肌梗塞),日本以脑血管疗变和肾病变死亡率为高,半数糖尿病性肾病发生肾功衰竭。这里对糖尿病患者微血管病变和大血管病变以及两者的关系进行探讨有重大
From the era of diabetic coma infection through the era of vascular disease now. Death from coma after the discovery of insulin in 1922 drastically decreased. Since 1944, there have been fewer antibiotic deaths due to infection. The cause of death from cardiovascular disease is now as high as 75%. Japan recently statistics of the cause of death of diabetic patients, due to heart, brain, renal vascular disease caused by 40 to 50%. Unlike the United States, which is the cause of death from diabetes mellitus in Japan, death in the United States is mainly due to coronary heart disease (myocardial infarction). In Japan, mortality from cerebrovascular disease and nephropathy is high, and renal failure occurs in half of diabetic nephropathy. Here for the microvascular disease and macrovascular disease in patients with diabetes and the relationship between the two major