环丙沙星是第三代喹诺酮类抗菌药；具有抗菌作用强，抗菌谱广，副作用少等优点，被临床广泛应用。 我院制剂中心配制过程中发现部分制剂有大量的针状结晶出现，这些针状在用力振摇后会消失，稍静置后又复出现，但经放置数天后可自行消失。 为此，我们做了多方面的观察与试验， Ciprofloxacin is the third generation of quinolone antibacterial drugs; has strong antibacterial activity, broad antibacterial spectrum, fewer side effects, etc., are widely used clinically. During preparation of our institute’s preparation center, a large amount of acicular crystals appeared in some preparations. These acicular forms disappeared when they were forcibly shaken. After a little restitution, they appeared again, but disappeared after being placed for several days. To this end, we have done a wide range of observations and experiments,