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目的了解扬州市艾滋病抗病毒治疗患者停药比例及原因,为制订针对性措施提供依据。方法对2004~2015年扬州市艾滋病抗病毒治疗停药患者的信息进行统计分析。结果累计抗病毒治疗艾滋病患者733例,其中78例终止治疗。男性停药比例高于女性(P>0.05);40~49岁停药比例为14.03%,高于其他年龄组(<30、30~39、≥50岁)停药比例(分别为6.67%、6.29%、12.10%)(P<0.05);已婚患者停药比例为13.15%,高于其他情况(未婚、离异或丧偶停药比例分别为4.60%、8.70%)(P<0.01);经血液/血制品、异性、同性、注射吸毒及不详途径传播的患者,停药比例分别为40.00%、13.01%、6.45%、37.50%、20.00%(P<0.01);服药后0~6、7~12、13~24、25~36、37~48、≥49个月,停药比例分别为17.33%、12.17%、9.15%、6.92%、11.48%、6.45%(P<0.05)。结论扬州市艾滋病抗病毒治疗停药病例的主要特征是异性感染、男性、已婚、中老年人群。
Objective To understand the proportion of patients with anti-HIV treatment in Yangzhou City and the reasons for their discontinuation, and to provide evidence for the development of targeted measures. Methods The data of patients with anti-HIV treatment in Yangzhou from 2004 to 2015 were analyzed statistically. Results A total of 733 AIDS patients were treated with antiviral therapy, 78 of whom discontinued treatment. The proportion of withdrawal from males was higher than that from females (P> 0.05). The rates of withdrawal from 40 to 49 were 14.03%, higher than those from other age groups (<30,30 to 39, ≥50 years) (6.67% 6.29% and 12.10% respectively) (P <0.05). The rate of withdrawal from married patients was 13.15%, higher than other cases (4.60%, 8.70%, respectively) Patients with blood / blood products, heterosexuality, same-sex, injecting drug use and unknown routes of transmission were 40.00%, 13.01%, 6.45%, 37.50% and 20.00% respectively (P <0.01) ~ 12,13 ~ 24,25 ~ 36,37 ~ 48, ≥49 months. The withdrawal rates were 17.33%, 12.17%, 9.15%, 6.92%, 11.48% and 6.45%, respectively (P 0. 05). Conclusion The main characteristics of anti-HIV treatment withdrawal cases in Yangzhou are heterosexual infection, male, married and middle-aged and elderly people.