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目的:通过对三阴性乳腺癌(TNBC)与非三阴性乳腺癌(non-TNBC)超声表现对比分析,总结三阴性乳腺癌声像图特征。方法:分析比较经手术或病理穿刺活检证实的TNBC 33例(35个病灶)及non-TNBC 82例(86个病灶)的术前超声表现,同时与病理结果相对照。结果:肿块后方回声增强在TNBC组与non-TNBC组比较中具有显著差异性(P<0.05),其它声像图特征如病灶的大小、纵横比、毛刺或分叶征、钙化灶、血流分级、血流速度、血流阻力指数两组比较无统计学差异。而淋巴结转移率non-TNBC组高于TNBC组(P<0.05)。结论:乳腺癌肿块后方回声增强及淋巴结低转移在TNBC与non-TNBC比较中具有显著差异性,可为筛查TNBC提供线索。
OBJECTIVE: To summarize the ultrasonographic features of triple negative breast cancer (TNBC) and non-triple negative breast cancer (non-TNBC). Methods: Preoperative ultrasound findings of 33 cases (35 lesions) of TNBC and 82 cases (86 lesions) of non-TNBC confirmed by surgery or pathological biopsy were analyzed and compared with those of pathological results. Results: Echogenicity of the posterior mass was significantly different between TNBC group and non-TNBC group (P <0.05). Other sonographic features such as lesion size, aspect ratio, burr or lobulation, calcification, blood flow Grading, blood flow velocity, blood flow resistance index was no significant difference between the two groups. The lymph node metastasis rate in non-TNBC group was higher than that in TNBC group (P <0.05). CONCLUSIONS: The enhancement of posterior echo and lymph node metastasis in breast cancer patients has significant difference between TNBC and non-TNBC, which can provide clues for TNBC screening.