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Acute promyelocytic leukemia(APL)is a special leukemia accounting for above 10%of adult acute myeloid leukemia.The t(15;17)(q22;q21)is a specific chromosome reciprocal translocation of APL,resulting in the generation of a fusion gene between a retinoic acid receptor alpha(RARα)and promyelocytic leukemia(PML)at the molecular level.Many research demonstrate that PML/RARa fusion gene can be regarded as the
Acute promyelocytic leukemia (APL) is a special leukemia accounting for above 10% of adult acute myeloid leukemia. T (15; 17) (q22; q21) is a specific chromosome reciprocal translocation of APL, resulting in the generation of a fusion gene between a retinoic acid receptor alpha (RARα) and promyelocytic leukemia (PML) at the molecular level. Many research demonstrates that PML / RARa fusion gene can be considered as the