EFFECTS OF GALLIUM AND ITS COMBINATION WITH SELENIUM ON MOUSE S_180 SARCOMA AND BONE GALLIUM CONTENT

来源 :Journal of Xi'an Medical University | 被引量 : 0次 | 上传用户:jslj
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Kunming female mice were used and S180 sarcoma cells were transplanted subeutaneously into right anterior armpit or the mice. The mice were divided into three groups randomly, and orally administered with water, gallium chloride and GaCl3+ Na2SeO3 respectively for 2 weeks. After that,the tumors and foreleg bones were taken out for study. The experimental results showed that oral administration with gallium chloride-could inhibit the growth or S180 sarcoma in mice and the tumor morphology was changed. Selenium could accelerate the gallium entering into bone. This fact might supply a new clue to further clinical application of gallium and selenium. Kunming female mice were used and S180 sarcoma cells were transplanted subeutaneously into right anterior armpit or the mice. The mice were divided into three groups randomly, and orally administered with water, gallium chloride and GaCl3 + Na2SeO3 respectively for 2 weeks. After that, the tumors The experimental results showed that oral administration with gallium chloride-could inhibit the growth or S180 sarcoma in mice and the tumor morphology was changed. new clue to further clinical application of gallium and selenium.
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