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自60年代初期以来,促性腺激素一直成功地用以治疗由于激素异常而导致的不育夫妇,特别是排卵功能障碍精子发生困难。早期妊娠失败、雄激素缺乏导致的性欲衰退以及最近体外受精中产生的问题,通过注射尿或垂体来源的促性腺激素制品均得到有效的治疗。但同时也始终存在着一些问题未能解决如缺乏稳定可靠的激素供应,以及由于缺乏纯化制品或FSH和LH的比率变化,治疗方案中的灵活性有限。
Since the early 1960s, gonadotropins have been successfully used to treat infertile couples due to hormonal abnormalities, especially ovulation dysfunction. Failure of early pregnancy, loss of libido due to androgen deficiency, and recent problems with in vitro fertilization are effectively treated by injection of gonadotropin products of urine or pituitary gland. But at the same time, there are always some problems that can not be solved such as the lack of a stable and reliable supply of hormones and limited flexibility in the treatment regimen due to the lack of purification products or changes in the ratio of FSH and LH.