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目的：比较维生素Ｋ＿１与哌替啶治疗肾绞痛的疗效。方法：维生素Ｋ＿１２０ｍｇ加５０％葡萄糖液２０ｍＬ静脉缓慢推注；哌替啶７５ｍｇ加阿托品０．５ｍｇ，ｉｍ；各治疗４０例肾绞痛病人，共８０例（男性４６例，女性３４例，年龄４３±ｓ１６ａ）。结果：维生素Ｋ＿１组的总有效率是９０％，与哌替啶组（９５％）无显著差异（Ｐ＞０．０５），但后者的药物不良反应明显，且有成瘾之虑。结论：维生素Ｋ＿１治疗肾绞痛疗效与哌替啶相似，但前者安全、无成瘾性，有应用价值。关键词
Objective: To compare the efficacy of vitamin K_1 and pethidine in the treatment of renal colic. Methods: Vitamin K_120mg plus 50% glucose solution 20mL intravenous bolus injection; pethidine 75mg plus atropine 0.5mg, im; Treatment of 40 cases of renal colic in patients with a total of 80 cases (46 males and 34 females, age 43 ± s16a). Results: The total effective rate of vitamin K_1 group was 90%, which was not significantly different from that of 95% of the pethidine group (P> 0.05). However, the adverse drug reactions of the latter were obvious and addicted. Conclusion: The efficacy of vitamin K_1 in treating renal colic is similar to that of pethidine, but the former is safe and non-addictive and has application value. Key words