甲状腺良性肿瘤微波消融和手术切除的对照研究

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目的对比甲状腺良性肿瘤采用微波消融和手术切除的治疗效果。方法 80例甲状腺良性肿瘤患者,按照治疗方式的不同分为研究组及对照组,各40例。研究组采用微波消融治疗,对照组采用手术切除治疗。比较两者患者的治疗效果。结果术前,两组患者的白介素-6、C反应蛋白、肿瘤坏死因子-α水平对比,差异均无统计学意义(P>0.05);术后,研究组患者的白介素-6、C反应蛋白、肿瘤坏死因子-α水平均低于对照组,差异均具有统计学意义(P<0.01)。研究组患者的手术时间、住院时间短于对照组,手术出血量少于对照组,差异均具有统计学意义(P<0.05)。两组患者的肿瘤清除率对比,差异无统计学意义(P>0.05)。研究组并发症发生率为2.5%,低于对照组的15.0%,差异具有统计学意义(P<0.05)。研究组甲状腺功能减退率为5.0%,低于对照组的92.5%,差异具有统计学意义(P<0.05)。研究组满意度为95.0%,高于对照组的45.0%,差异具有统计学意义(P<0.05)。结论甲状腺良性肿瘤采用微波消融的治疗效果显著优于手术切除,值得在临床推广应用。 Objective To compare the therapeutic effect of microwave ablation and surgical resection of benign thyroid tumors. Methods Eighty patients with thyroid benign tumor were divided into study group and control group according to the different treatment methods, 40 cases in each. The study group was treated with microwave ablation and the control group with surgical resection. Compare the treatment effect of both patients. Results There were no significant differences in the levels of interleukin-6, C-reactive protein and tumor necrosis factor-α between the two groups before operation (P> 0.05). After operation, the levels of interleukin-6, C-reactive protein , Tumor necrosis factor-α levels were lower than the control group, the difference was statistically significant (P <0.01). The study group’s operation time and hospitalization time were shorter than those of the control group, and the amount of bleeding during operation was less than that of the control group. The differences were statistically significant (P <0.05). There was no significant difference in tumor clearance between the two groups (P> 0.05). The complication rate of the study group was 2.5%, which was lower than that of the control group (15.0%), the difference was statistically significant (P <0.05). The rate of hypothyroidism in the study group was 5.0%, which was lower than that in the control group (92.5%), the difference was statistically significant (P <0.05). The satisfaction rate of the study group was 95.0%, which was higher than that of the control group (45.0%), the difference was statistically significant (P <0.05). Conclusion The treatment of benign thyroid tumors by microwave ablation is significantly better than surgical resection, which is worthy of clinical application.
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