Wilmarth 在1887年首先描述原始脑纹部位存在异常的脑裂。yakovlev 和 Wa-dsworth 后来将脑裂从病理学上较广泛地介绍了先天性脑裂外表的破坏性与脑损害孔洞脑畸形之间那些神经细胞被移动的原因。最初不理解这个先天性异常,开始从严重残废儿童身上而取得的病理标本。Page 等描述了一个疑有脑裂的儿童用血管描记象和脑室充气 X 线摄影法来研究,而后被外科探查术所证实。在四岁时,这位儿童患严重的精神运动性智力迟钝。Williams 等描述了临床 CT 对三位儿童确诊为脑裂。但是这三位病人两大脑半球均有血管梗阻。又发现11例脑裂病人的 CT特征是一致的,而且神经系统发育异常得到充分证实. Wilmarth first described in 1887 the presence of an abnormal brain crack in the original brain pattern. Yakovlev and Wa-dsworth later introduced the pathology of the brain cleft to more broadly describe the reason that those nerve cells are removed between the destructive congenital dehiscence of the brain and the cerebral lesion of the brain. At first, I did not understand this congenital anomaly and began to get the pathological specimens from the severely disabled children. Page et al describe a suspected schizophrenic children with vascular imaging and ventricular inflatable radiography to study, and was confirmed by surgical exploration. At the age of four, the child suffered from severe mental retardation. Williams et al described the clinical CT diagnosis of three children with brain dehiscence. However, these three patients had vascular obstruction in both hemispheres. Also found that 11 cases of patients with cracked brain CT features are consistent, and neurodevelopmental abnormalities have been fully confirmed.