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目的:观察津力达颗粒联合胰岛素治疗2型糖尿病临床疗效。方法:将确诊为2型糖尿病的患者116例随机分为治疗组与对照组各58例。治疗组在使用胰岛素的基础上口服津力达颗粒,对照组单纯使用胰岛素皮下注射,治疗1月后比较两组疗效。结果:两组治疗后空腹血糖(FPG)、餐后2 h血糖(2 hPG)、糖化血红蛋白(HbA1c)均较治疗前明显降低,差异有统计学意义(P<0.01);血糖达标时间、胰岛素用量、低血糖发生率比较,治疗组优于对照组(P<0.01);总有效率比较,治疗组优于对照组(P<0.05)。结论:津力达颗粒联合胰岛素治疗2型糖尿病能增强胰岛素敏感性,有效控制血糖,还可以减少胰岛素的用量,减少低血糖的发生,改善临床症状。
Objective: To observe the clinical efficacy of “Jinlida granule combined with insulin” in the treatment of type 2 diabetes mellitus. Methods: One hundred and sixty-six patients diagnosed with type 2 diabetes were randomly divided into treatment group (58 cases) and control group (58 cases). The treatment group was treated with insulin on the basis of oral Jin Li Da particles, the control group simply using insulin subcutaneous injection, the treatment of one month after the two groups were compared. Results: The fasting plasma glucose (FPG), 2 h postprandial blood glucose (2 hPG) and HbA1c in both groups were significantly lower than those before treatment (P <0.01) Dosage and incidence of hypoglycemia in the treatment group were better than those in the control group (P <0.01). The total effective rate was better in the treatment group than in the control group (P <0.05). Conclusion: The combination of Jinlida granules and insulin can enhance insulin sensitivity and control blood sugar effectively. It can also reduce the dosage of insulin, reduce the incidence of hypoglycemia and improve the clinical symptoms.