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[Hirasawa M et al:Infect Immun 27(3):915,1980(英文)] 变形链球菌已被确认为龋齿的主要致病菌。龋齿牙面菌斑的形成与变形链球菌产生的能从蔗糖合成可溶性和不溶性葡聚糖的转葡糖基酶(GTF)有关。从变形链球菌67/5株衍变的突变株C4具有GTF缺陷,不能合
[Hirasawa M et al: Infect Immun 27 (3): 915, 1980 (English)] Streptococcus mutans have been identified as the major pathogens of dental caries. Cariogenic plaque formation is associated with Streptococcus mutans (GTF) that produces soluble and insoluble glucan from sucrose. Mutant C4 mutated from Streptococcus mutans 67/5 strain has GTF deficiency and can not be combined