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本文就洋地黄在心力衰竭中的应用作一讨论。一、洋地黄的作用原理洋地黄对心肌的作用,归纳起来有以下4点;①正性肌力作用。机理迄今未明。多数学者认为,洋地黄可使心肌细胞膜—横管系统内流的钙离子增多,收缩蛋白更有力地收缩;②负性频率怍用。治疗量洋地黄可增加颈动脉窦压力感受器的敏感性,反射性地兴奋迷走神经,使窦性心律减慢;③负性传导作用。治疗量洋地黄由于反身于性地使迷走神经居优势,因而可使房室传导减慢。但大剂量应用时可出现非迷走性
This article discusses the use of digitalis in heart failure. First, the role of digitalis Principles of digitalis on the role of the heart, summed up the following 4:00; ① positive inotropic effect. The mechanism is not yet known. Most scholars believe that digitalis can make the myocardial cell membrane - horizontal tube system influx of calcium ions, contractile contraction more strongly; ② negative frequency 怍 use. The treatment of digitalis can increase the sensitivity of the carotid sinus baroreceptor reflex excited vagus nerve so that sinus rhythm slowed; ③ negative conduction. The treatment of digitalis due to the retrograde nature of the vagus nerve dominant, which can slow atrioventricular conduction. However, high-dose application may appear non-vagal sex