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目的匹多莫德口服液联合孟鲁司特钠及干扰素雾化辅助治疗反复毛细支气管炎的疗效。方法选取2012年4月—2014年3月灵台县人民医院收治的反复毛细支气管炎患儿80例作为研究对象,随机分为对照组与观察组,各40例。对照组患儿予以常规治疗,观察组患儿予以匹多莫德口服液联合孟鲁司特钠及干扰素雾化辅助治疗。比较两组患儿临床疗效、咳嗽消失时间、喘憋缓解时间、肺部啰音消失时间。结果观察组患儿总有效率为92.5%,高于对照组的70.0%,差异有统计学意义(P<0.05);观察组患儿咳嗽消失时间、喘憋缓解时间、肺部啰音消失时间短于对照组,差异均有统计学意义(P<0.05)。结论匹多莫德口服液联合孟鲁司特钠及干扰素雾化辅助治疗反复毛细支气管炎的疗效显著,可缩短治疗时间,快速缓解临床症状。
Objective Efficacy of pidotimod oral solution combined with montelukast sodium and interferon nebulization in the treatment of recurrent bronchiolitis. Methods Eighty children with recurrent bronchiolitis admitted from Lingtai County People’s Hospital from April 2012 to March 2014 were selected as study subjects and randomly divided into control group and observation group, 40 cases each. Children in the control group were given routine treatment. The children in the observation group were treated with Pidotimod oral solution combined with montelukast sodium and interferon nebulization. The clinical efficacy, cough disappearing time, asthmatic relief time and pulmonary rales disappeared were compared between the two groups. Results The total effective rate in the observation group was 92.5%, which was higher than that in the control group (70.0%, P <0.05). The cough disappear time, wheezing relieving time, pulmonary rales disappearance time Shorter than the control group, the difference was statistically significant (P <0.05). Conclusion Pidotimod oral liquid combined with montelukast sodium and interferon nebulization in the treatment of recurrent bronchiolitis have significant curative effect, which can shorten the treatment time and quickly relieve the clinical symptoms.