目的通过一种新的简便的方法合成顺、反式3,4′,5三羟基二苯乙烯。方法化合物3和4发生缩合反应形成二苯乙烯骨架,然后经过水解、脱羧、异构化、脱甲基得到反式3,4′,5三羟基二苯乙烯(白藜芦醇),将其进行光异构化得到顺式3,4′,5三羟基二苯乙烯。结果以化合物3和4为起始原料合成顺、反式3,4′,5三羟基二苯乙烯。结论以价廉易得的工业化原料为起始物,建立了一种多羟基顺、反式二苯乙烯类化合物的简易合成方法。 Aims To synthesize cis, trans 3,4 ’, 5 trihydroxystilbene by a new and simple method. Methods Compounds 3 and 4 undergo a condensation reaction to form a stilbene skeleton, which is then hydrolyzed, decarboxylated, isomerized and demethylated to give trans 3,4 ’, 5-trihydroxystilbene (resveratrol) The photoisomerization is carried out to obtain cis 3,4 ’, 5 trihydroxy stilbene. Results Cis, trans 3,4 ’, 5 trihydroxystilbene were synthesized using compounds 3 and 4 as starting materials. CONCLUSION A simple and easy synthesis method of polyhydroxy cis, trans stilbene compounds was established by using cheap and readily available industrial raw materials as starting materials.