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肾病综合征患者钙代谢紊乱。长期认为低钙血症常由低蛋白血症所致。近来已注意到小肠钙吸收减少、低离子钙血症、循环钙二醇水平降低以及继发性甲状腺功能亢进,而钙三醇循环水平可能正常或降低,亦可发生骨质脱钙和组织学异常改变。本文在一组GFR(肾小球滤过率)正常的肾病小儿观察到钙代谢和骨质钙化的异常。方法与结果:58例2—20岁(平均10.1岁)的肾病患者(男性39例),复发次数为79次,缓解82次。肾活检发现19例肾小球微小病变,6例肾小球系膜增生,5例局限和节段性肾小球硬化,1例膜性肾小
Nephrotic syndrome patients with disorders of calcium metabolism. Long-term hypocalcemia often caused by hypoproteinemia. It has recently been noted that there is a decrease in intestinal calcium absorption, hypocalcemia, a decrease in circulating calcium diol levels and secondary hyperthyroidism, while calcitriol cycle levels may be normal or decreased, and decalcification and histology may also occur Abnormal changes. In this paper, a group of GFR (glomerular filtration rate) normal nephrotic children observed calcium metabolism and bone calcification abnormalities. Methods and Results: Fifty-eight patients with nephropathy (39 males) aged 2-20 years (average 10.1 years) had 79 relapses and 82 remissions. Renal biopsy showed 19 cases of glomerular lesions, 6 cases of mesangial proliferation, 5 cases of localized and segmental glomerulosclerosis, 1 case of membranous renal