论文部分内容阅读
目的:探讨宫颈分泌物中高磷酸化IGFBP-1、血清中CRP、宫颈指数在早产预测中的价值。方法:对西丽人民医院诊治的91例先兆早产孕妇检测其宫颈分泌物中IGFBP-1、血清中C-反应蛋白,同时经会阴超声检测宫颈指数。随访至分娩,分析多指标联合应用在早产预测中的价值。结果:IGFBP-1、宫颈指数的阳性组中早产发生率明显高于阴性组(P<0.01),该两指标联合应用对早产的阳性预测值明显提高(P<0.01)。血清CRP在早产组与足月产组间无统计学差异(P>0.05)。结论:宫颈分泌物IGFBP-1联合宫颈指数可提高对早产预测的准确性。
Objective: To investigate the value of hyperphosphorylated IGFBP-1 in cervical secretions, serum CRP and cervical index in the prediction of preterm labor. Methods: Ninety-one pregnant women with threatened preterm labor diagnosed and treated in Xili People’s Hospital were tested for IGFBP-1 in cervical secretions and C-reactive protein in serum. Cervical index was measured by perineal ultrasonography. Follow-up to childbirth, analysis of the value of multi-index combination in preterm labor prediction. Results: The incidence of preterm birth in IGFBP-1 and cervical index positive group was significantly higher than that in negative group (P <0.01). The positive predictive value of combined application of these two indexes for preterm birth was significantly increased (P <0.01). There was no significant difference in serum CRP between preterm and full term (P> 0.05). Conclusion: Cervical secretions IGFBP-1 combined with cervical index can improve the accuracy of the prediction of preterm birth.