论文部分内容阅读
视网膜下间隙系指外以视网膜色素上皮(RPE)、内以外界膜为界的一个间隙,近端以位于视乳头周围的Kuhnt中间组织为界,远端以位于距齿缘的色素上皮和Muller细胞之间的细胞接头为界。每一个界限都有其特殊结构及对疾病的不同反应。作为视网膜下间隙外界的色素上皮也是血-视网膜屏障两个主要地点之一;另一个位于视网膜毛细血管内皮。RPE及其封闭小带(zonulae occludens)可阻止血浆蛋白和血流中其他大分子进入视网膜下间隙。然而从脉络膜循环带来的葡萄糖、氧和其他营养物质则可通过色素上皮供给视网膜外层。营养物质经过色素上皮的运输与经
Under the subretinal space refers to the outside of the retinal pigment epithelium (RPE), the outside world within the membrane as a boundary, the proximal end of the Kuhnt located in the middle of the optic nerve around the organization, the distal to the edge located in the pigment epithelium and Muller Cell junctions between cells are bounded. Each boundary has its own special structure and different responses to the disease. The pigment epithelium, which is the outer part of the subretinal space, is also one of the two major sites of the blood-retinal barrier; the other is located in the retinal capillary endothelium. RPE and its zonulae occludens prevent plasma proteins and other macromolecules in the bloodstream from entering the subretinal space. However, glucose, oxygen and other nutrients from the choroidal circulation can be supplied to the outer retinal layer through the pigment epithelium. Nutrients through the pigment epithelium transport and after