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目的 分析浙江省武义县1992-2016年梅毒流行趋势和特征,为制订有效的防治策略提供依据.方法 收集1992-2016年的梅毒疫情资料进行描述性分析.结果 武义县1992-2016年共报告梅毒病例3 847例,年均报告发病率为45.80/10万,逐年递增至2010年达到503例的高峰,2007-2011年共报告梅毒1 886例,占全部梅毒病例的49.02％,自2007年以来,梅毒成为当地主要的性病类型(48.52％和48.30％).梅毒病例中男女性别比为1∶1.26;发病年龄集中在20～49岁(2 892例,占75.18％);职业以农民为主(1 989例,占51.70％).病例以Ⅰ期梅毒和隐性梅毒为主,传播途径以非婚性接触为主(2 959例,占76.92％),胎传梅毒自2001年报道以来,已累计报告132例.结论 武义县梅毒疫情呈现持续上升趋势,应继续广泛开展重点人群的干预措施以控制梅毒流行.“,”Objective To analyze the epidemiological characteristics of syphilis in Wuyi from 1992 to 2016 and provide scientific basis for formulating prevention and control measures.Methods Date on the prevalence of syphilis form 1992 to 2016 were collected and analyzed.Results From 1992 to 2016,a total of 3 847 syphilis cases were reported in Wuyi county.The average annual increment was 45.80/100 000.It was indicated that the annual specific incidence rate had been greatly increasing and reached the peak in 2010 (503 cases).A total of 1 886 syphilis cases were reported during 2007 and 2011,of which accounted for 49.02％ of 25 years.Since 2007,syphilis had become the main type of venereal disease(48.52％ and 48.30％) in Wuyi.More cases occurred among female than male with the gender ratio of 1:1.26.The 20 to 49-year-old adults were affected seriously (2 892 cases,75.18％).The peasant was seen in term of job category (1 989 cases,51.70％).Most of the patients were cases in first stage and recessivity,and the route of transmission was mainly sexual contact outside marriage (2 959 cases,76.92％).Fetal infection since reported from 2001,had added up to 132 cases.Conclusions The incidence of syphilis increases in Wuyi.Therefore,the intervening measure on focus groups are required to control the epidemic of syphilis.