论文部分内容阅读
目的:观察降钙素原(PCT)、白细胞计数(WBC)以及C反应蛋白(CRP)在儿童肺炎的诊断及判断疗效上价值。方法:按照随机数表法从2013年6月-2015年6月在河源市源城区上城社区卫生服务中心进行治疗的肺炎儿童中随机抽出70例,并且按照不同病因分为细菌性肺炎组患儿37例,病毒性肺炎组患儿19例,支原体肺炎组患儿14例,比较治疗前及治疗7 d后细菌性肺炎组、病毒性肺炎组、支原体肺炎组中PCT水平、WBC计数及CRP水平的变化情况,并进一步分析3项检查的联合运用对于儿童肺炎诊断及疗效判断的价值。结果:细菌性肺炎组的PCT水平,WBC计数,CRP水平的阳性率明显高于病毒性肺炎组与支原体肺炎组,差异具有统计学意义(P<0.05);PCT阳性率方面,细菌性肺炎组与支原体肺炎组与其它指标相比偏高,病毒性肺炎组血清PCT阳性率与其它指标相比偏低;治疗后细菌性肺炎组及支原体肺炎组PCT水平、WBC计数及CRP水平明显下降,病毒性肺炎组PCT水平、WBC计数及CRP水平下降不明显。结论:PCT能很好鉴别肺炎患儿病因,PCT、WBC及CRP联合检测在儿童肺炎的鉴别诊断及疗效监测有重要意义,对指导抗生素的应用及疗效评价具有较高价值。
Objective: To observe the value of procalcitonin (PCT), white blood cell count (WBC) and C-reactive protein (CRP) in the diagnosis and diagnosis of children pneumonia. Methods: According to random number table, 70 patients were randomly selected from pneumonia children who were treated in Shangcheng Community Health Service Center, Yuancheng District, Heyuan City from June 2013 to June 2015. According to different causes, they were divided into bacterial pneumonia group 37 children, 19 children with viral pneumonia and 14 children with mycoplasma pneumonia. The levels of PCT, WBC and CRP in bacterial pneumonia group, viral pneumonia group and mycoplasma pneumonia group before and after treatment for 7 days were compared Level changes, and further analysis of the combined use of three tests for the diagnosis of children with pneumonia and curative effect judgments value. Results: The positive rates of PCT, WBC and CRP in bacterial pneumonia group were significantly higher than those in viral pneumonia group and mycoplasma pneumonia group (P <0.05). In the positive rate of PCT, bacterial pneumonia group Compared with other indicators, mycoplasma pneumonia and other indicators of mycoplasma pneumonia were higher than those of other indicators in viral pneumonia group. PCT, WBC count and CRP levels in bacterial pneumonia group and mycoplasma pneumonia group were significantly decreased after treatment, Pneumonia group PCT levels, WBC count and CRP levels decreased not obvious. Conclusion: PCT can identify the etiology of children with pneumonia. The combined detection of PCT, WBC and CRP is of great significance in the differential diagnosis and curative effect monitoring of childhood pneumonia. It is of great value in guiding the application of antibiotics and evaluating the curative effect.