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目的:探讨手足口病的临床转归情况。方法:选取我院2009年5月~2012年5月收治的手足口病患儿146例,随机分为轻症组和重症组,各73例,轻症组予对症治疗和抗病毒治疗。重症组给心电监护,抗感染、抗病毒、退热以及补充维生素,同时采取抢救措施。探讨2组患儿的转归情况。结果:2组WBC计数、中性粒细胞计数以及血清肌酸激酶同工酶比较,差异均有明显统计学意义,P<0.01。73例轻症组患儿经过积极的治疗均痊愈出院,住院时间为5.00±1.24天,无1例转为重症病例,重症组患儿73例。治愈72例,无1例死亡病例。结论:对手足口病患儿要根据病情进行治疗,对于重症患儿或者有发生重症危险因素的患儿要早期发现,并给以积极的治疗,控制病情进展,提高救治的成功率,降低手足口病的死亡率。
Objective: To investigate the clinical outcome of hand-foot-mouth disease. Methods: A total of 146 children with HFMD were enrolled in our hospital from May 2009 to May 2012, and randomly divided into mild and severe cases, 73 cases in each group. The patients in mild group were given symptomatic and antiviral treatment. Severe group to ECG monitoring, anti-infective, anti-virus, antipyretics and vitamin supplements, while taking rescue measures. To investigate the outcome of two groups of children. Results: There were significant differences in WBC count, neutrophil count and serum creatine kinase isoenzymes between the two groups (P <0.01). 73 cases of mild disease group were cured after active treatment and were discharged Time was 5.00 ± 1.24 days, no one to severe cases, severe cases 73 cases of children. 72 cases were cured without any deaths. Conclusion: The patients with foot-mouth disease should be treated according to their condition. Early detection should be made for children with severe illness or severe risk factors. Active treatment should be given to control the progress of the disease, improve the success rate of treatment, Mouth disease mortality.