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目的:观察硫辛酸治疗糖尿病周围神经病变的疗效。方法:将100名糖尿病周围神经病变患者随机分为2组:对照组(50例)和治疗组(50例)。对照组应用维生素B1针100mg联合维生素B12针500ug肌肉注射,1天1次,治疗组应用硫辛酸0.6g+生理盐水250ml避光静脉点滴,1天1次,14天为1个疗程,观察2组患者TSS评分及神经传导速度变化情况。结果:治疗后2组患者的TSS评分及神经传导速度变化均较前有改善,且治疗组优于对照组(P<0.05)。结论:硫辛酸治疗糖尿病周围神经病变疗效满意,值得临床推广。
Objective: To observe the efficacy of lipoic acid in the treatment of diabetic peripheral neuropathy. Methods: One hundred patients with diabetic peripheral neuropathy were randomly divided into two groups: control group (50 cases) and treatment group (50 cases). In the control group, 100mg vitamin B1 needle and 500mg vitamin B12 needle were injected intramuscularly once a day. The patients in the treatment group were treated with lipoic acid 0.6g + saline 250ml, intravenous drip once a day for 14 days for 1 course. Patient TSS score and nerve conduction velocity changes. Results: After treatment, TSS score and nerve conduction velocity of two groups were improved compared with the former, and the treatment group was better than the control group (P <0.05). Conclusion: Lipoic acid is effective in treating diabetic peripheral neuropathy and is worthy of clinical promotion.