静脉输液为临床给药的常用手段,目前国内的静脉输液瓶针(穿刺针)针头,为尖端锲形开孔之构造。针头欲插入药液中,其锲形面首先需要穿过橡胶塞。由于瓶针针头开孔方向与针头锲形面穿过橡胶塞的插入方向相重合,因此在穿插过程中,橡胶塞成份会不可避免地脱落到输液器中,再通过输液过程流入人体。我们知道,橡胶塞是由橡胶及不溶性微粒(如ZnO、CaCO_3等)组成,且橡胶塞上方在压盖时压有铝屑,下面的绦纶膜在高温高压灭菌时能与橡胶颗粒粘连,因此,瓶针针头穿过橡胶塞时,则橡胶颗粒、不溶性微粒及薄膜碎片都可带 Intravenous infusion is a commonly used means of clinical administration, the current domestic intravenous infusion bottle needle (needle) needle, the tip of the wedge-shaped hole structure. Needle inserted into the liquid, the wedge-shaped surface first need to cross the rubber plug. Because the opening direction of the bottle needle and needle coincides with the insertion direction of the needle wedge through the rubber plug, the rubber plug will inevitably fall into the infusion set and then flow into the human body through the infusion process during the insertion process. We know that the rubber stopper is composed of rubber and insoluble particles (such as ZnO, CaCO_3, etc.), and the top of the rubber stopper pressed aluminum gland, the following polyester film under high temperature autoclave with rubber particles adhesion, Therefore, the bottle needle needle through the rubber plug, then the rubber particles, insoluble particles and film fragments can be brought