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目的分析脑梗死患者伴脑微出血(CMBs)的相关危险因素。方法连续纳入75例脑梗死患者,进行磁敏感成像(SWI)检查,根据有无CMBs分为CMBs组及NCMBs组(无微出血组)。记录患者的一般临床资料及生化检查结果,并行相关危险因素分析。结果共检出36例CMBs患者,2组在年龄、饮酒、高血压、腔隙性梗死、卒中史、抗血小板治疗方面差异均有统计学意义(P<0.01或P<0.05);Logistic回归分析显示年龄、高血压病、饮酒、卒中史、抗血小板治疗是CMBs独立危险因素(P<0.01或P<0.05)。结论脑梗死患者高龄、高血压病、饮酒、卒中史、抗血小板治疗可能是发生CMBs的独立危险因素。
Objective To analyze the related risk factors of cerebral micro-hemorrhage (CMBs) in patients with cerebral infarction. Methods 75 consecutive patients with cerebral infarction were enrolled in this study. Magnetic resonance imaging (SWI) was performed. According to the presence or absence of CMBs, the patients were divided into CMBs group and NCMBs group (without micro-bleeding group). Record the general clinical data of patients and biochemical test results, parallel analysis of risk factors. Results A total of 36 patients with CMBs were detected. There were significant differences in age, alcohol consumption, hypertension, lacunar infarction, stroke history and antiplatelet therapy between the two groups (P <0.01 or P <0.05). Logistic regression analysis Age, hypertension, alcohol consumption, history of stroke and antiplatelet therapy were independent risk factors for CMBs (P <0.01 or P <0.05). Conclusions Elderly patients with hypertension, alcoholism, stroke history and antiplatelet therapy may be independent risk factors of CMBs in patients with cerebral infarction.