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目的探讨有冠状动脉慢血流现象的患者阵发性心房颤动(paroxysmal atrial fibrillation PAF)与冠脉慢血流的关系。方法选择冠状动脉造影正常但存在冠脉慢血流的患者66例为I组,男38例,女28例。冠脉造影正常无冠脉慢血流的患者88例为II组,男51例,女37例。冠状动脉血流情况按照校正的TIMI血流分级方法评估。所有患者在住院后随访1年,行动态心电图检查有无PAF。P波离散度(Pd)从体表12导联心电图测得。计算PAF在各组的发病率。结果两组年龄、性别、高血压病、心力衰竭、糖尿病、高脂血症、抽烟史等均无明显统计学差异。I组患者Pd与II组比较明显延长(39.3±12.6)vs21.5±10.8milliseconds,P<0.01).,PAF发病率明显比II组升高(18.2%vs7.9%,P<0.01)结论在有冠状动脉慢血流现象的患者中患者P波离散度较对照组明显延长,阵发性心房颤动发病率升高。
Objective To investigate the relationship between paroxysmal atrial fibrillation (PAF) and coronary blood flow in patients with coronary arterial slow flow. Methods Sixty-six patients with normal coronary artery angiography but with slow coronary flow were selected as Group I, 38 males and 28 females. 88 patients with normal coronary artery without coronary flow underwent coronary angiography were Group II, including 51 males and 37 females. Coronary flow was assessed according to a modified TIMI flow classification. All patients were followed up for 1 year after hospitalization, and ambulatory electrocardiogram was used to check for PAF. P wave dispersion (Pd) measured from body surface lead 12 ECG. The incidence of PAF in each group was calculated. Results There was no significant difference in age, gender, hypertension, heart failure, diabetes, hyperlipidemia and smoking history between the two groups. Compared with group II, the incidence of PAF in group I was significantly longer than that in group II (39.3 ± 12.6 vs 21.5 ± 10.8milliseconds, P <0.01), and the incidence of PAF was significantly higher than that in group II (18.2% vs 7.9%, P <0.01) P wave dispersion in patients with slow blood flow in patients with coronary artery was significantly longer than the control group, the incidence of paroxysmal atrial fibrillation increased.