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目的:对消化性溃疡患者分别进行奥美拉唑以及泮托拉唑治疗,并观察其临床应用效果。方法:选取我院2015年4月~2016年4月100例患者,随机分为两组,即观察组与对照组,观察组:50例患者,每日早餐前空腹口服泮托拉唑40mg,每日一次,持续治疗30d,对照组:50例患者每日早餐前空腹口服奥美拉唑20mg,每日一次,持续治疗30d。结果 :观察组患者在治疗(3.5±1.4)d左右腹痛基本消失,对照组在治疗(3.7±1.2)d左右,患者腹痛基本消失,两组比较差异无统计学意义(P>0.05)。经计算,观察组的总有效率为90%,对照组的总有效率为80%,两组比较无明显差异,无统计学意义(P>0.05)。结论 :使用泮托拉唑和奥美拉唑相较而言,使用泮托拉唑对于消化性溃疡的治疗效果更佳,安全风险更低。
Objective: To treat patients with peptic ulcer separately with omeprazole and pantoprazole, and to observe its clinical effect. Methods: One hundred patients in our hospital from April 2015 to April 2016 were randomly divided into two groups: the observation group and the control group. In the observation group, 50 patients were given orally fasting pantoprazole 40 mg daily before breakfast, Once a day, continuous treatment for 30 days, control group: 50 patients were orally administered omeprazole 20 mg daily before breakfast, once daily for 30 days. Results: The abdominal pain disappeared in the observation group (3.5 ± 1.4) d, while in the control group (3.7 ± 1.2) d, the abdominal pain disappeared. There was no significant difference between the two groups (P> 0.05). The total effective rate of the observation group was 90% and that of the control group was 80%. There was no significant difference between the two groups (P> 0.05). Conclusion: The use of pantoprazole compared with omeprazole compared with the use of pantoprazole for the treatment of peptic ulcer better effect, lower security risk.