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1970年至1993年共放射治疗骨巨细胞瘤22例。单纯放疗3例,术后放疗14例,术后复发放疗5例。肿瘤剂量<48Gy6例,40~50Gy13例,>50Gy3例。全组5年生存率95.%(20/21),10年生存率87.5%的(14/16)。2例分别于放疗后半年及7年死于肿瘤肺转移。20例至今健在,最长者已存活26年,均能正常生活及工作,未发现恶变成照射区内第二恶性肿瘤发生。我们认为对不能手术、手术不彻底、术后复发及病理分级商的骨巨细胞瘤思考。放射治疗为一种有效的治疗手段。
From 1970 to 1993, 22 cases of giant cell tumor of bone were treated with radiotherapy. Radiotherapy alone in 3 cases, postoperative radiotherapy in 14 cases, postoperative recurrence and radiotherapy in 5 cases. Tumor dose <48Gy6 cases, 40 ~ 50Gy13 cases,> 50Gy3 cases. The 5-year overall survival rate of 95. % (20 of 21), 10-year survival rate of 87.5% (14/16). Two patients died of tumor lung metastasis in six months and seven years after radiotherapy. Twenty cases have survived so far and the oldest have survived for 26 years, both of which can live and work normally. No malignant transformation has been found in the second malignant tumor in the irradiated area. We do not think surgery, surgery is not complete, postoperative recurrence and pathological grade of bone giant cell tumor thinking. Radiation therapy is an effective treatment.