论文部分内容阅读
观察五联疗法治疗急性坏死性胰腺炎 (ANP)并发多器官功能衰竭 (MOF)的疗效。全部病例 (A PACHEⅡ评分 13～ 33分 )术后入住ICU ,采用 :①早期机械通气支持治疗 ;②全胃肠外营养支持治疗 ;③大黄鼻饲或 /和灌肠 ;④持续大剂量腹腔灌洗 ;⑤早期应用强效、广谱抗生素。 17例患者中 ,治愈或好转 14例 ,死亡 3例 ,病死率 17.6 %。其中 2个器官衰竭者 6例 ,无死亡 ;3个器官衰竭者 4例 ,死亡 1例 ,病死率 2 5 .0 % ;4个以上器官衰竭者 7例 ,死亡 2例 ,病死率 2 8.6 %。提示 ,在积极治疗原发病的基础上 ,五联疗法能显著降低ANP合并MOF的病死率。
To observe the curative effect of pentotherapy on acute necrotizing pancreatitis (ANP) complicated with multiple organ failure (MOF). All patients (A PACHE Ⅱ score 13 to 33 points) admitted to ICU after surgery, using: ① early mechanical ventilation support; ② total parenteral nutrition support; ③ rhubarb nasal feeding or / and enema; ④ sustained high-dose lavage; ⑤ early strong, broad-spectrum antibiotics. Of the 17 patients, 14 were cured or improved, 3 died, and the case fatality rate was 17.6%. Among them, there were 6 cases of 2 organ failure without death, 4 cases of 3 organ failure, 1 case of death, the case fatality rate was 25.0%, 7 cases of 4 or more organ failure, 2 cases died and the case fatality rate was 2 8.6% . Tip, in the active treatment of the primary disease on the basis of five-therapy can significantly reduce the mortality of ANP combined MOF.