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目的探讨广西壮族自治区(广西)3个农村地区痛风患者发病与代谢综合征(MS)的相关性。方法采用1∶1配对的病例对照研究设计方法,于2015年收集广西3个县379例痛风病例,以同一区域的人群为对照,分析调查对象中MS的患病率以及痛风与MS各相关指标的相关关系。结果痛风组MS患病率为33.25%、非痛风组MS患病率为11.87%,痛风组高于非痛风组(χ~2=49.546,P<0.01)。两组MS相关指标均值和阳性率差异有统计学意义。相关因素分层后,痛风组MS的患病风险明显高于非痛风人群。痛风组MS诊断标准中异常项检出率随着项目增多呈上升趋势。多因素logistic回归分析显示,超重和(或)肥胖、高舒张压和甘油三酯升高为痛风的独立危险因素。结论痛风患者中MS的患病率增高,痛风与MS各相关指标密切相关,对MS及各相关指标的积极干预可减少痛风的发病。
Objective To investigate the relationship between the incidence of gout and metabolic syndrome (MS) in three rural areas of Guangxi Zhuang Autonomous Region (Guangxi). Methods A 1: 1 matched case-control study was designed. In 2015, 379 cases of gout were collected from 3 counties in Guangxi. The prevalence of MS in the surveyed subjects and the related indicators of MS and gout The relationship between. Results The prevalence of MS in gout group was 33.25%. The prevalence of MS in non-gout group was 11.87%. The gout group was higher than non-gout group (χ ~ 2 = 49.546, P <0.01). There was significant difference between mean and positive rate of MS related index in two groups. After stratification, the prevalence of MS in gout group was significantly higher than that in non-gout group. Gout group MS diagnostic criteria for the detection rate of anomalies increased as the project is on the rise. Multivariate logistic regression analysis showed that overweight and / or obesity, high diastolic blood pressure and elevated triglycerides were independent risk factors for gout. Conclusions The prevalence of MS in gout patients is high. Gout is closely related to various related indicators of MS. Active intervention on MS and related indicators can reduce the incidence of gout.