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用全反式维甲酸（ATRA）配合藻酸双脂钠（PSS）诱导分化治疗急性早幼粒细胞白血病（APL）18例,CR率88.9%。通过与不用PSS组对比,表明可以减少治疗中DIC的发生率和降低DIC的相关死亡率。
Treatment of acute promyelocytic leukemia (APL) with all trans-retinoic acid (ATRA) and alginic acid sodium (PSS) induced differentiation in 18 patients, the CR rate was 88.9%. By comparing with no PSS group, it was shown that the incidence of DIC during treatment and the related mortality of DIC can be reduced.