论文部分内容阅读
本文研究观察了小鼠静脉摄入重核裂变产物~(147)Pm后不同间隔时间对生殖细胞染色体畸变和精子(主要是无钩精子)畸形的诱变效应,实验结果发现~(147)Pm可诱发精原细胞染色体结构畸变;随着机体受内污染时间的延长,染色体畸变率和多倍体细胞也有所增加,同时~(147)Pm也可诱发初级精母细胞产生染色体断片和易位,形成多价体。染色体断片率随~(147)Pm辐照时间的延长而升高。而多价体只在内污染10天后的实验组中出现。
In this study, the mutagenic effects of 147-Pm heavy-core fission products in mice on chromosomal aberrations and spermatozoa (mainly unhooking spermatozoa) aberrations at different intervals were investigated. The results of the experiment showed that ~(147)Pm It can induce the chromosome structure distortion of spermatogonia. With the prolongation of the internal contamination time, chromosome aberration rate and polyploid cells increase, and ~(147)Pm can also induce chromosome fragmentation and translocation of primary spermatocytes. , forming a multivalent body. Chromosomal fragmentation rate increased with the irradiation time of ~(147)Pm. The multivalent body only appeared in the experimental group after 10 days of internal contamination.