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应用氩离子激光照射人体离体动脉粥样硬化斑块(简称斑块)208个,定量分析其照射功率、照射时间、照射距离、传输介质和斑块性质等因素在斑块消蚀过程中对周围组织损害的情况。结果表明;在一定照射功率和照射时间内,周围组织损害的严重度主要与传输介质和照射距离两因素改变有关:以全血为传输介质时损害最严重,生理盐水则最轻;在照射距离中以0mm组最严重,2mm组最轻。由此提示适当增加照射功率或延长照射时间以有效地气化斑块,可能是安全可行的。
A total of 208 human isolated atherosclerotic plaques (referred to as plaques) were irradiated with argon ion laser and quantitatively analyzed the effects of irradiation power, irradiation time, irradiation distance, transmission medium and plaque properties on plaque erosion Damage to the surrounding tissue. The results showed that the severity of the surrounding tissue damage was mainly related to the change of transmission medium and irradiation distance under certain irradiation power and irradiation time. The damage was the most serious when the whole blood was the transmission medium and the lightest was the normal saline. In 0mm group the most serious, 2mm group the lightest. This suggests that it may be safe and feasible to appropriately increase the irradiation power or prolong the irradiation time to effectively vaporize the plaque.