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新生儿单纯疱疹病毒感染的发病率接近1/7500,当脑被侵袭时,在急性期有很高的并发症和死亡率,即使存活,也常留下广泛的神经损伤.以往曾用碘苷治疗,因无效且毒性太大而停用.本文报告用左旋咪唑治疗播散性新生儿单纯疱疹1例获成功.一足月女婴,产后健康,第二天,除掌蹠外全身发生水疱脓疱性损害,第四天损害开始消退,因全身性强直阵挛性发作,而于第六天住院.体检:显示水疱脓疱性损害,神经科检查正常,脑脊液检查:白细胞17/mm~3、蛋白50mg/d1、葡萄糖40mg/d1,直接
The incidence of neonatal herpes simplex virus infection is close to 1/7500 and when the brain is attacked, there is a high complication and mortality in the acute phase, leaving extensive neurological damage even if it survives. In the past, Treatment, because of ineffective and too toxic to disable .This article reports the use of levamisole disseminated neonatal herpes simplex in 1 case was successful .A full-term baby girl, postpartum health, the next day, in addition to palmoplantar blister pus Blister damage, the fourth day the damage began to subside, due to generalized tonic clonic seizures, and hospitalized on the sixth day. Physical examination: blister pustular damage, neurological examination was normal, cerebrospinal fluid examination: white blood cells 17 / mm ~ 3 , Protein 50mg / d1, glucose 40mg / d1, directly