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目的 探讨本地区上消化道多原发性癌的某些临床特点。方法 回顾性分析我院 2 4年内 119例上消化道多原发性癌的临床资料。结果 发病高峰年龄为 5 1～ 70岁 ,男性多于女性 ,体力劳动者较脑力劳动者高。同时性和异时性上消化道多原发性癌两癌灶发生的平均间隔时间分别为 0 12个月和 4 7年 ;同时性和异时性食管多原发性癌、胃多原发性癌和食管、胃多原发性癌的好发部位分别为食管中段 -下段、胃窦 -贲门和食管中段 -胃体 ;癌灶手术后病理检查以食管鳞状细胞癌和胃粘液腺癌多见。结论 内镜检查时仔细观察上消化道全程 ,结合每处癌灶及癌灶间粘膜活检有助于提高上消化道多原发性癌的诊断水平
Objective To investigate the clinical features of multiple primary cancers in the upper gastrointestinal tract in this area. Methods The clinical data of 119 cases of multiple primary carcinoma of the upper digestive tract in our hospital during 24 years were retrospectively analyzed. Results The peak age of onset was 51 to 70 years old, more men than women, manual workers than mental workers. Simultaneous and heterochronous upper gastrointestinal multiple primary carcinoma of the two foci of the occurrence of the average interval were 0 12 months and 47 years; simultaneous and heterotopic esophageal multiple primary cancer, multiple gastric origin Cancer and esophageal, gastric multiple primary cancer were found in the middle part of the esophagus - the lower segment, gastric antrum - the middle of the esophagus - gastric body; foci postoperative pathological examination with esophageal squamous cell carcinoma and gastric mucinous adenocarcinoma More common. Conclusions Endoscopic examination of the entire upper gastrointestinal tract, combined with each of the foci and mucosal biopsy can help improve the diagnosis of multiple primary cancer of the upper digestive tract