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应用小鼠骨髓细胞姐妹染色单体交换(SCE)及微核试验对鸡腿蘑进行遗传毒理检测。结果表明:用鸡腿蘑浸提液处理过的小鼠,其骨髓细胞微核率及SCE频率与阴性对照组比较差异不显著(P>0.05),而与阳性对照组相比,差异极显著(P<0.01)。这表明,鸡腿蘑无致畸变作用。
The chicken bone marrow cell sister chromatid exchange (SCE) and micronucleus test were used to detect the genotoxicity of Coprinus comatus. The results showed that there was no significant difference in the frequency of micronuclei and the frequency of SCE among the mice treated with the extract from Juglans Regia (P> 0.05), while the difference was significant compared with the positive control group P <0.01). This shows that Coprinus act non-deformity.