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目的对比替硝唑联合阿奇霉素或头孢噻肟钠治疗急性盆腔炎临床效果。方法将120例急性盆腔炎患者随机分为观察组和对照组,每组60例。观察组采用替硝唑联合阿奇霉素治疗,对照组采用替硝唑联合头孢噻肟钠治疗。观察2组治疗效果、症状改善时间及不良反应。结果观察组治疗有效率为95.00%,对照组为93.33%,2组比较差异无统计学意义(P>0.05);2组症状改善时间和不良反应发生率比较差异无统计学意义(P>0.05)。结论替硝唑联合阿奇霉素或头孢噻肟钠治疗急性盆腔炎均可获得良好效果,症状改善快速,不良反应可控,临床应根据药敏试验结果选择治疗方案。
Objective To compare the clinical efficacy of tinidazole and azithromycin or cefotaxime sodium in the treatment of acute pelvic inflammatory disease. Methods 120 patients with acute pelvic inflammatory disease were randomly divided into observation group and control group, 60 cases in each group. The observation group was treated with tinidazole and azithromycin, while the control group was treated with tinidazole and cefotaxime sodium. The treatment effect, symptom improvement time and adverse reaction were observed in the two groups. Results The effective rate was 95.00% in the observation group and 93.33% in the control group. There was no significant difference between the two groups (P> 0.05). There was no significant difference between the two groups in symptom improvement time and incidence of adverse reactions (P> 0.05 ). Conclusion Tinidazole combined with azithromycin or cefotaxime sodium for the treatment of acute pelvic inflammatory disease can get good results, rapid improvement of symptoms and adverse reactions can be controlled, clinical trials should be based on drug susceptibility testing results.