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从流行病学上讲,人乳头状瘤病毒(HPV)感染和乙肝病毒(HBV)感染都与恶性转化紧密相关.可是现在还未能证实两者之间的因果关系.与这些病毒有关的癌肿,生殖器癌,尤其是宫颈癌以及肝细胞癌均有数十年的潜伏期.这表明,病毒感染的生物作用是多种致癌因素中一个必需因素,而促使受感染细胞向恶性转化的机制尚未得到阐明.人乳头状瘤病毒与生殖器癌乳头状瘤病毒几乎无例外地是嗜上皮细胞
Epidemiologically, human papillomavirus (HPV) infection and hepatitis B virus (HBV) infection are closely related to malignant transformation. However, the causal relationship between the two has not yet been confirmed. The cancer associated with these viruses Swollen, genital cancers, especially cervical cancers and hepatocellular carcinomas, have a latency period of several decades. This suggests that the biological role of viral infections is an essential factor in many carcinogenic factors, and the mechanisms that promote the malignant transformation of infected cells have not yet been identified. It is clarified that human papilloma virus and genital cancer papilloma virus are almost exclusively epithelial cells.