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采用ＡｇＮＯＲ技术对３１例混合瘤和３例恶性混合瘤进行观察。结果发现，混合瘤不同个体的ＡｇＮＯＲ特性存在差异，１．５８～４．１７／细胞核，１９／３１例混合瘤瘤细胞核内ＡｓＮＯＲ量少、粒粗，形态规则，提示这些瘤细胞增殖缓慢，可能代表混合瘤的良性病例。９／３１混合瘤出现成簇分布的ＡｇＮＯＲ颗粒，大小形态不一，分布不均，ＨＥ染色见较多核分裂象，提示其瘤细胞增殖活跃，可能具有潜在恶性行为。３／３１混合瘤与恶性混合瘤的ＡｇＮＯＲ特征相似，应作恶变高危对象处理。此外，良恶性混合瘤之间和混合瘤复发与非复发组之间，其ＡｇＮＯＲ存在非常显著的差异（Ｐ＜０．０１），表明混合瘤术后复发除与术式选择，术者水平有关外，还与其增殖特性有关，临床上对复发而再次手术的病例，应作低度恶性肿瘤对待。
31 cases of mixed tumor and 3 cases of malignant mixed tumor were observed by AgNOR technique. The results showed that the characteristics of AgNOR in different individuals of mixed tumor were different. The number of AsNOR in nuclei of 1.58 ~ 4.17 / nucleus and 19/31 mixed neoplasms was small, with coarse grains and regular morphology, suggesting that the proliferation of these tumor cells may be slow On behalf of benign mixed tumor cases. 9/31 mixed tumor appeared clustered distribution of AgNOR particles, the size of the shape, uneven distribution, HE staining more mitotic figures, suggesting that the proliferation of tumor cells may have potentially malignant behavior. 3/31 mixed tumor and malignant mixed tumor AgNOR characteristics similar to malignant transformation should be high-risk object treatment. In addition, there was a very significant difference in the AgNOR between benign and malignant mixed tumors and between recurrent and non-recurrent mixed tumors (P <0.01), indicating that recurrence of mixed tumors is related to the choice of operative type and level of the surgeon In addition, but also with its proliferation characteristics, the clinical recurrence and reoperation cases, should be treated as low-grade cancer.