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目的 探讨分析端粒酶在乳腺肿瘤组织的表达对乳腺癌早期诊断的临床价值。方法 应用免疫组化方法 ,对 170例病人分别进行检测。结果 端粒酶的表达与乳腺癌的临床分期 ,腋淋巴结转移密切相关 (P <0 0 1) ,特别是在乳腺癌前病变中有表达。结论 端粒酶对乳腺癌的早期诊断具有一定的价值。
Objective To investigate the clinical value of telomerase expression in breast tumors in early diagnosis of breast cancer. Methods Immunohistochemical methods were used to detect 170 patients. Results The expression of telomerase was closely related to clinical stage and axillary lymph node metastasis of breast cancer (P < 0.01), especially in precancerous lesions. Conclusion Telomerase has a certain value in the early diagnosis of breast cancer.