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目的:观察康艾注射液对老年晚期非小细胞肺癌(NSCLC)含顺铂方案化疗的影响。方法:55例老年晚期非小细胞肺癌患者均采用含顺铂方案化疗,其中治疗组28例加用康艾注射液,比较两组近期疗效、化疗后生活质量评价、血液毒性反应情况。结果:两组病例近期疗效比较,治疗组与对照组相似(P>0.05);化疗后患者生活质量评价治疗组优于对照组(P<0.05),治疗组化疗后血液毒性反应低于对照组,差异有显著性(P<0.05)。结论:康艾注射液治疗老年晚期非小细胞肺癌,在稳定病灶、改善临床症状、提高患者生活质量等方面显示出一定优势。
Objective: To observe the effect of Kangai Injection on cisplatin-containing chemotherapy in elderly patients with advanced non-small cell lung cancer (NSCLC). Methods: 55 cases of advanced non-small cell lung cancer patients were treated with cisplatin chemotherapy, including 28 cases of treatment group with Kang Ai injection, the two groups of short-term efficacy, quality of life after chemotherapy evaluation, hematological toxicity. Results: The curative effect of the two groups was similar to that of the control group (P> 0.05). The quality of life of patients in the treatment group was better than that of the control group (P <0.05), and the hematological toxicity in the treatment group was lower than that in the control group , The difference was significant (P <0.05). Conclusion: Kangai injection in the treatment of elderly patients with advanced non-small cell lung cancer showed some advantages in stabilizing the lesions, improving clinical symptoms and improving the quality of life of patients.