目的脑胶质瘤手术效果不佳的一个重要原因就是无法界定和示踪正常脑组织与肿瘤组织的边缘。近年来,科学家将拉曼成像技术运用到脑胶质瘤及其边缘的检测中,并取得初步成果。本文综述了利用拉曼成像技术检测脑胶质瘤的研究进展,并对其在生物医药领域中的应用作了展望。 Purpose An important reason for the poor performance of glioma surgery is the inability to define and track the edges of normal brain tissue and tumor tissue. In recent years, scientists have applied Raman imaging technology to the detection of glioma and its margins, and achieved initial results. This review summarizes the research progress of using Raman imaging to detect gliomas and gives a prospect of its application in biomedicine.