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目的 探讨多电极射频 (RFA)治疗肝癌的作用。方法 采用RFA治疗肝癌 18例 ,其中肝细胞性肝癌 12例 ,转移性肝癌 6例。B超引导经皮穿刺射频治疗 8例 ,术中射频治疗 10例 ,共 2 4个结节 ,直径 2～ 8cm ,平均 4.2cm。结果 18例患者术后 1d肝功能轻到中度升高 ,7d恢复正常。随访 3～ 8个月 (平均 4.2个月 ) ,2 1个结节完全坏死 ,局部复发结节 3个 ,经再次RFA治疗有效。无一例严重并发症发生。结论 多电极射频治疗是一种安全、有效且依从性好的肝癌治疗手段 ,开腹射频治疗可有效预防其并发症的发生 ,但射频治疗的远期疗效还需要进一步的研究。
Objective To investigate the role of multi-electrode radiofrequency (RFA) in the treatment of liver cancer. Methods 18 cases of liver cancer were treated with RFA, including 12 cases of hepatocellular carcinoma and 6 cases of metastatic liver cancer. B ultrasound guided percutaneous radiofrequency radiotherapy in 8 cases, intraoperative radiofrequency treatment in 10 cases, a total of 24 nodules, diameter 2 ~ 8cm, an average of 4.2cm. Results The liver function was mildly to moderately elevated in 1 of 18 patients, and returned to normal in 7 days. Followed up for 3 to 8 months (average 4.2 months), 21 nodules were completely necrotic, and 3 were locally recurrent nodules. The RFA treatment was effective again. No serious complication occurred. Conclusion Multi-electrode RF therapy is a safe, effective and well-tolerated treatment for liver cancer. Open radiofrequency treatment can effectively prevent the occurrence of complications, but the long-term efficacy of radiofrequency treatment needs further study.